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Michal Marczyk, Joanna Polanska, "Analysis of mass spectra of a different cancers including spectra alignment as a pre-processing step." Short abstract: Recently mass spectrometry has become the most frequently chosen technique for the analysis of complex protein samples. Such measurements can be used to identify disease-related patterns, which hold potential for early diagnosis, prognosis or drug target research. The key features in a mass spectrum are its peaks. In order to locate the peaks and quantify their intensities, several pre-processing steps are required. We believe that spectra alignment should be one of them. In this study we will present results of analysis of mass spectra of a 3 different cancers: lung cancer, large intestine cancer and head and neck regions cancer. We use a common classifier to identify differential expressions in comparison to healthy group. |